Alpha GPC is a highly effective nootropic that supports several functions in the body, including cognition and memory, neural and cellular membrane support, and neurochemical balance. This compound is also effective at increasing growth hormone production and strength.
Alpha GPC has been the subject of several studies examining its impact on strength and human performance. One such study, published in the Journal of the International Society of Sports Nutrition, found that administering Alpha-GPC 90 minutes prior to weight training sessions led to an increase in growth hormone production and peak bench press force.
The Effect of 6 Days of Alpha-GPC on Isometric Strength
In this study led by David Bellar, Nina R. LeBlanc, and Brian Campbell, the impact of 6 days of Alpha GPC supplementation on isometric strength was evaluated. The results showed that the Alpha-GPC treatment group experienced a significantly greater increase in isometric mid thigh pull peak force compared to the placebo group (98.8 ± 236.9 N vs -39.0 ± 170.9 N).
This study suggests that Alpha GPC supplementation can lead to an increase in lower body force production. Sport performance coaches may consider adding Alpha GPC to the diet of speed and power athletes to enhance their muscle performance. The findings of this study and the prior research on the effects of Alpha GPC on strength highlight the potential of this supplement as a valuable addition to a sports performance regimen.
Alpha GPC has also been shown to have a positive impact on growth hormone. A study published in the Journal of the International Society of Sports Nutrition found that administering Alpha GPC 90 minutes before weight training sessions increased growth hormone production and peak bench press force. The study used a single dose of 600 mg of AlphaGPC and found that compared to baseline (pre) values, peak GH increased 44-fold during AlphaGPC administration (from 0.19 ± 0.06 to 8.4 ± 2.1 ng/mL) versus 2.6-fold during placebo.
Peak GH increased 44-fold during Alpha GPC administration versus 2.6-fold during placebo!
Another study published in Nutrition also investigated the effects of Alpha GPC on GH secretion and found that it enhances GH secretion and fat oxidation in young adults. The study found that Alpha GPC is an effective tool in promoting GH secretion and can be a beneficial supplement for young adults.
Balancing Mood & Brain Function
Choline and Acetylcholine play a crucial role in maintaining cognitive health and neurochemical balance. For instance, research shows a correlation between low plasma choline levels and increased anxiety. Supplementation with Alpha GPC (150 mg/kg) has been shown to increase dopamine and Acetylcholine levels in the frontal cortex and cerebellum in rats, providing further evidence of its potential in maintaining neurochemical balance.
Choline and Acetylcholine are widely regarded as reliable indicators of cognitive health and overall brain function. Research supports their role as powerful nootropics, impacting neuronal excitability, synaptic transmission, plasticity, and coordinated firing of neurons. By modifying the response of neuronal networks throughout the brain, ACh plays a crucial role in shaping the brain's response to internal and external stimuli.
In addition to its cognitive benefits, Alpha GPC also supports neural and cellular membrane health. Choline and Acetylcholine levels are often used as biomarkers for long-term cognitive health and neurochemical balance, and preliminary research suggests that choline may play a role in regulating anxiety levels. Alpha GPC supplementation has been shown to increase dopamine and Acetylcholine levels in the frontal cortex and cerebellum of rats, but these effects were not seen with an equal dose of choline from CDP-choline.
Alpha GPC primarily metabolizes into choline and glycerophosphate, with choline serving as a precursor to the neurotransmitter acetylcholine (ACh). Acetylcholine is essential for supporting memory formation and recall, learning ability, and concentration/focus.
Acetylcholine plays a crucial role in memory and cognition by enhancing the brain's response to sensory stimuli. It does so by altering neuronal excitability and influencing synaptic transmission and plasticity throughout the body, particularly in the prefrontal cortex, the area associated with short-term working memory.
Alpha GPC has been shown to support cognitive abilities, especially in the elderly who may experience normal age-related memory decline. It stands out from other compounds like choline and CDP-choline as it directly raises choline levels in the brain and potentially contributes to neural plasticity and acetylcholinesterase inhibition.
Acetylcholinesterase is an enzyme that breaks down the neurotransmitter acetylcholine. By inhibiting this enzyme, Alpha GPC can help increase the levels of acetylcholine in the brain.
Studies have found that at high doses, Alpha GPC can significantly improve cognitive abilities more effectively than other compounds.
So! What have we learned?
Alpha GPC is a highly effective cognitive enhancer that supports several functions in the body, including cognition and memory, neural and cellular membrane support, and neurochemical balance.
It's also effective at increasing growth hormone production and strength, making it a highly versatile supplement.
Increased focus, strength & growth hormone? Yes please! Alpha GPC is a multi-tasking nootropic superstar and one of the key ingredients in our Keto Brainz Nootropic creamer. Each serving gets you 300mg of Alpha GPC!